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Aspirin overdose antidote
Aspirin overdose antidote








Pts stay alkalemic until end, acidemia is indicative of high morbidity.

aspirin overdose antidote

  • Initially respiratory alkalosis from direct effects on respiratory center, then metabolic acidosis from ketones, salicylate, and lactate.
  • The NCPE of this toxin can be confused with pneumonia.
  • Vomiting (central and peripheral causes) and Gastritis.
  • Hyperglycemia becomes hypoglycemia when can not keep up with demand.
  • Burns off all glucose, so gluconeogenesis with ketonemia.
  • Used as an aborted experiment for heat production, in cold soldiers in Russia, as well as fat burning tool.) Other agents that uncouple ox phos are dinitrophenol and pentrophenol.
  • Uncouples oxidative phosphorylation giving lactic acidosis and hyperthermia (the uncoupling, rather than blocking leads to heat production.
  • Hyperventilation from direct effects on the respiratory center.
  • aspirin overdose antidote

    1.4 g per cc in pure form, less in Bengay (also can be absorbed topically) Acetylsalicylic Acid and Methyl Salicylate (Oil of Wintergreen) from willow bark.










    Aspirin overdose antidote